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Study on the effect of RCM-104 in the treatment of obesity

George Binh Lenon et al.

January 2012

Overweight / obesity

The Chinese-Australian study investigated the efficacy and safety of the Chinese herbal medicine formula RCM-104, which is used in TCM for the treatment of obesity.

The sample of 117 overweight subjects was divided into two groups, each taking either four capsules of RCM-104 (n = 59) or placebo pills (n = 58).

The randomized, double-blind treatment was administered three times a day for twelve weeks. BW, BMI and WC, HC, WHR and BF were measured at the beginning of the study and every four weeks during treatment.

92 subjects were considered in the ITT analysis and the researchers found that weight, BMI and BF were reduced by 1.5 kg, 0.6 kg/m2 and 0.9% in the RCM-104 group, while the same values increased by 0.5 kg, 0.2 kg/m2 and 0.1% in the placebo group.

Adverse side effects were low in both groups. The RCM-104 treatment proved to be well tolerated and effective in the treatment of obesity in the course of this study.

The most important information on the study at a glance

Indications: Obesity
Institution: Traditional & Complementary Medicine Research Program, Health Innovations Research Institute, School of Health Sciences, RMIT University, Bundoora, VIC 3083, Australia
Title: Study on the effect of RCM-104 in the treatment of obesity
Brief description: A Chinese-Australian study shows that the Chinese herbal medicine RCM-104 is safe and effective for obesity.
Original title: Efficacy and Safety of a Chinese Herbal Medicine Formula (RCM-104) in the Management of Simple Obesity: A Randomized, Placebo-Controlled Clinical Trial
Link to the study: https://pubmed.ncbi.nlm.nih.gov/22550541/